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An opportunity for increased affinity might therefore come from utilising specific interactions with these terminal residues, although there would be an entropic penalty to their ordering

Evaluation of an synuclein sensitized dendritic cell based vaccine in a transgenic mouse model of Parkinson disease
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Dysbiosis, or the imbalance of gut microbial communities, can precipitate shifts in redox balance, leading to increased oxidative stress and contributing to various diseases, from metabolic disorders to inflammatory and neurodegenerative conditions

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36 Increased ROS can impair mitochondrial function 36, 190 and may be particularly significant in individuals with ASD because they have been shown, as a group, to be under higher oxidative stress and have reduced levels of antioxidants as compared with controls
