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This ERK-independent pathway may involve the RTK activation of phosphotidylinositol 3-kinase (PI3K)/Akt cascades (see below and Figs

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J Biochem Mol Toxicol 30:120127 [DOI] [PubMed] [Google Scholar] Jahovic N, ener G, evik H, Ersoy Y, Arbak S, Yeen B (2004) Amelioration of methotrexate-induced enteritis by melatonin in rats