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L-carnitine: Participants were treated with Carnitor brand or generics at a starting dose of 100 mg/kg/day divided BID, or 2 grams twice a day, whichever is smaller

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Coimmunoprecipitations For immunoprecipitation experiments, crude mitochondria preparations were lysed with 1 TEVP buffer 94 (10 mM Tris base, 5 mM NaF, 1 mM Na 3 VO 4 , 1 mM EDTA, 1 mM EGTA [pH 7.4]) supplemented with 0.5% Triton X-100 and protease inhibitors

Expert Opin Drug Discovery 9: 669686 R Core Team (2017) R: a language and environment for statistical computing