when were glp 1 agonists discovered The expanding landscape of GLP-1 medicines GLP1 agonists: current and future
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doi: 10.4161/cam.21054 60 CramerJVBenakisCLieszA

Also, Neves et al

However, to make GLP-1 analogs work well required solving two key challenges a high enough dose and making the drug last longer in our bodies i.e

A provider who knows when you plan to wean can help you prepare, discuss what to expect from treatment, and have a plan ready so you can start promptly when the time is right

Bunck, M.C

The key is that GLP-1 RA medications are long-lasting receptor agonists that have an effect lasting much longer than naturally produced GLP-1
