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A particularly challenging combination is that of conventional and Spitz nevus because the presence of large epithelioid cells can lead to a diagnosis of melanoma [17]

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10.1098/rstb.2012.0212 [DOI] [PMC free article] [PubMed] [Google Scholar]

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The substitutions referred to are norleucine at position 4 and D-phenylalanine at position 7
