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Since it cant be sold as a regulated medication, most of what is available online is sold as an unregulated research chemical. This means there is no oversight on purity or quality, and products can be contaminated with heavy metals or bacteria

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In this potentially life-threatening disease, the intrinsic factor for the absorption of vitamin B12 in the stomach is completely absent, resulting in a severe long-term vitamin B12 deficiency with consequences for blood formation, neurological disorders and an inflamed tongue

doi:10.1016/s0928-4257(97)89474-0 28

It extends the GLOW blend with the addition of KPV for anti-inflammatory signaling research