glutathione buffer half life Glutathione-Related Enzymes and Proteins: A Review GSSG plays an essential role in cellular redox balance Human IgG Fc-engineering for enhanced

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For this reason, GSH administration should be limited to its approved indications (e.g., platin-induced neurotoxicity) or to clinical/preclinical studies where applicable

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-Glucuronide-based ADCs derived from this framework demonstrated favorable developability profiles, including high achievable drug-to-antibody ratios, reduced aggregation driven by the hydrophilic carbohydrate motif, and improved plasma stability relative to conventional protease-cleavable dipeptide linkers

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