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S.AfsharzadehD.et al (2021)

Moreover, it is worth to underline the need of exploring the role of iron-mediated oxidative damage through Fenton reaction to further ascertain the contribution of mitochondrial dysfunction and iron accumulation to the progression and pathologic development of age-related diseases

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Nat Rev Mol Cell Biol 2001

This complex activates caspase-9, which subsequently triggers the activation of downstream caspases-3 and 7, consequently initiating a cascade of caspase reactions that leads to apoptosis (Fig
