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For this purpose, we administered a hydrogen-rich and alkaline water treatment orally to mice that had undergone a 2-week treatment with H 2 O 2 , which induced a general state of sickness related to a marked redox imbalance at both systemic and single-organ levels

For HT-qPCR analysis, 22 gene sequences were selected

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Because of this metabolic rewiring, cancer cells typically display the accumulation of abnormally high levels of lactate with consequent acidification of the tumor microenvironment (TME) and immunosuppression [3]

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Expert Review of Neurotherapeutics 2010