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Herzenberg LA, et al

The brains were harvested and post-fixed in 4% paraformaldehyde, followed by dehydration in 20% sucrose-PBS and then 30% sucrose-PBS
MLC1 protein: a likely link between leukodystrophies and brain channelopathies

Emerging therapeutic strategies for SLE extend beyond B cell depletion to target CD4 follicular helper T (Tfh) cells: E4BP4 inhibits Tfh differentiation by repressing BCL-6 transcription via recruitment of HDAC1 and EZH2, while impaired E4BP4 function and IFN-Idriven IL-21/IFN- production promote Tfh expansion and autoreactive B cell responses, supporting Tfh-directed CAR-T approaches (54, 55)
Serine hydroxymethyltransferase: role of glu75 and evidence that serine is cleaved by a retroaldol mechanism

Xia, Z.-W