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Structureactivity relationships (compounds 179 , 181 184 , 379 ) have confirmed the key roles of the disulfide bond, thiophene ring dihydrothiophene and thiazoline in bioactivities

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In March 2022, Tsvetkov et al.s research demonstrated that excessive intracellular copper induces the aggregation of dihydrolipoyllysine-residue acetyltransferase (DLAT), which is associated with the mitochondrial tricarboxylic acid (TCA) cycle, and is related to mitochondrial activity, resulting in a novel form of copper poisoning-induced cell death

Digestion of NAPQI-GST Reductive alkylation was performed using 10 L DTT (25 mM

By systematically analyzing these factors, this study hopes to facilitate preventive intervention and mitigation of early cataract formation and provide new thoughts and solutions for clinical practice