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Furthermore, a specific deletion of Tyr 1138 in LepRb or STAT3 in LepRb-expressing neurons leads to hyperphagia and obesity similar to the phenotype observed in db/db mice [29], suggesting that Tyr 1138 in STAT3 is vital for leptin action

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BDNF regulation of synaptic structure, function, and plasticity

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Having too much of any neurotransmitter is just as bad as not having enough and can lead to unpleasant side effects like headaches, stomach aches, tremors, or serious complications like serotonin syndrome.40 Serotonin This neurotransmitter is responsible for our mood, sleep, and digestion, and it stabilizes other neurotransmitters