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The rate of decrease in the absorbance is directly proportional to the GPX activity in the sample

doi: 10.3390/toxins12090578, 195

244 Using large-scale in vivo CRISPR screening technology, researchers have identified the E3 ligase Cop1 within breast cancer cells as an essential regulator of macrophage chemokine secretion

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Concurrently, Dox-induced ROS accumulation and damaged organelles activate the NOD-like receptor family pyrin domain-containing 3 (NLRP3) inflammasome, resulting in cleavage of pro-caspase-1, activation of caspase-1, and subsequent maturation and secretion of the pro-inflammatory cytokines interleukin-1 (IL-1) and interleukin-18 (IL-18)

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