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Chronic accumulation of biomass through aerobic glycolysis and the polyol pathway is responsible for retinopathy, nephropathy, and neuropathy next to all aforementioned diseases ( In line with the reviewed data, people suffering from metabolic syndrome (Mets) are susceptible to the development of many, if not all, CNCDs

[DOI] [PubMed] [Google Scholar] 85.Tokutake T., Ishikawa A., Yoshimura N., Miyashita A., Kuwano R., Nishizawa M., Ikeuchi T

In patients who receive supplementation, as in patients with known SPCD, close follow-up is therefore recommended to adjust supplementation when necessary

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DNA fragmentation Splitting of DNA strands into shorter pieces by endonucleolytic DNA cleavage at multiple sites

Kopitz, J., Holz, F