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Immunosuppressive effects of acrolein exposure were also seen in human T cells, in which acrolein directly alkylated Cys-61 and Arg-307 of NF-B1 (p50), significantly reducing binding to the promoters of IL-2, IL-10, TNF-, GMCSF, and IFN, with a notable exception being IL-8 (Lambert et al

Mucoadhesive chitosangum arabic nanoparticles enhance the absorption and antioxidant activity of quercetin in the intestinal cellular environment

However, these same pathways can theoretically accelerate tumor growth or reawaken dormant cancer cells in individuals with active malignancy or recent remission

eBioMedicine (2022) 76:103861

Association of oxidative stress biomarkers and antioxidant enzymatic activity in male infertility of North-East India

It activates Nrf2, a regulator of antioxidant defense, triggering comprehensive cellular protection strategies