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The competitive IRAP inhibitor 23 (HA08) enhances the numbers of dendritic spines in hippocampal cell cultures and HA08 treatment resulted in an increasing number of stubby and mushroom-like spines, a morphology typically associated with mature spines, which are believed to have strengthened synaptic connectivity

Mid-Phase: 375 mcg daily during Weeks 58

AOD-9604 also inhibits lipogenesis, the synthesis of new fat, adding a second metabolic angle

Selected References and Key Studies Pickart L, Margolina A

What patients should actually expect week by week follows a predictable pattern

However, if you have a sensitive gut, an overload of glutathione can cause a slight disruption to digestion, which is why experts suggest starting with a smaller dose and working your way up