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doi: 10.1038/s42255-023-00801-2 61 HallCJBoyleRHAstinJWFloresMVOehlersSHSandersonLEet al
10.1503/jpn.100057 J Psychiatry Neurosci
They can bind to free fatty acid receptors (FFARs) on immune cells, while butyrate, as a HDAC inhibitor, can upregulate the expression of anti-inflammatory genes and induce microglial polarization toward an anti-inflammatory phenotype (Zhao et al., 2022
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Cyclic dinucleotides, which are produced by the cyclic GMP-AMP synthase (cGAS) in response to cytosolic DNA, bind to STING at the ER
M., Tew, K
