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Using YMU1 as a lead, the compounds JMF2977 and JMF4073 were synthesized

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Backbone N-methylation of peptides: Advances in synthesis and applications in pharmaceutical drug development

When ROS are excessively accumulated, the equilibrium of E 2 metabolism is broken by: one, upregulating the expression of cytochrome P450, leading to the enrichment of redox-active catechol E 2 s, which continually induce ROS generation (59)

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