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these findings suggest that it prevents EMT from exerting its anti-fibrotic effects by affecting fibroblasts ( 3.5 Pneumonia In human lung epithelial cells (Calu3), andrographis paniculata extract and andrographolide exhibited strong anti-SARS-CoV-2 activity in a dose-dependent manner, with high safety and no obvious cytotoxicity (Zhu et al., 2013)

Hepcidin knockout mice fed with iron-rich diet develop chronic liver injury and liver fibrosis due to lysosomal iron overload

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Dopamine deficiency in the nigrostriatal pathway is one of the main causes of PD

While more clinical trials are needed, the current data indicate that polyphenol compounds hold promise as dietary interventions or lead compounds for novel therapeutics in PD