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Lipid hydroperoxides (LOOH) are reduced by GPX4 to non-toxic lipid alcohols, thereby preventing ferroptosis, an iron-dependent form of neuronal cell death (Bayr et al., 2020)

Deficiency of intestinal mucin-2 ameliorates experimental alcoholic liver disease in mice

82 NiaHTLiuHSeanoGDattaMJonesDRahbariNet al

10.3390/ijerph17228452 64

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Moreover, chronic stress exposure triggers systemic inflammatory activation through upregulation of pro-inflammatory cytokine cascades (Ravi et al., 2021)
