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10.1136/gutjnl-2014-308419 Gut

It enhances angiogenesis (the formation of new blood vessels), increases flexibility, and helps modulate inflammation

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As the work of Judah Folkman defined the induction of corneal neovascularization and angiogenesis that can lead to tumorigenesis [68], in the case of NO-system disturbances, as described by Moncada, the threatening chain of events is well-defined [191]

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After 1-2 months: Fine lines and wrinkles might start to noticeably fade as skin texture and elasticity begin to improve