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It is also important to note that states of GH-excess, such as acromegaly, are associated with muscle weakness and fatigue (Flitsch, Spitzner and Ludecke, 2000), suggesting that chronically elevated levels of GH or IGF-I have a deleterious effect on muscle

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Mass spectrometry Protein containing polyacrylamide gel slices were prepared for mass spectrometric analysis by 2 5 alternating washing steps with 10 mM HEPES, p H 6.8 in water and a 1:1 mixture (v/v) of 100 mM HEPES in water (p H 6.8) and acetonitrile

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and enhance exercise tolerance, allowing individuals to walk longer distances before experiencing discomfort