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Cleavage of Boc groups with 4 M HCl/dioxane followed by a coupling reaction with the -carboxyl group of the N -hydroxysuccinimide active ester of Boc-Glu--OtBu resulted in the corresponding glutathione disulfide-1,1- 13 C with fully protected N and C-terminals

Kanat O, Ertas H, Caner B

Of more than 100 cannabinoids in the plant, delta-9-tetrahydrocannabinol (THC) is the main psychoactive compound, which alters the mind or behavior

Despite demonstrated efficacy in vitro , curcumin's poor aqueous solubility, chemical instability at physiological pH, and extensive metabolism result in barely detectable plasma concentrations after oral administration (164167)

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For instance, titanium dioxide, previously regarded as a safe additive, has recently been implicated in genotoxicity, raising concerns about its safety