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Description
The most widely used system for conditional knockout (gene inactivation) is the Cre-lox system (4-6)
M.FranoisI
Abmart) in antibody dilution buffer (Beyotime, Shanghai, China) at 4C overnight
Normally it is associated with Keap1 (Kelch-like erythroid cell-derived protein with CNC homology (ECH) associated protein 1) in the cytoplasm, which mediates Nrf2 ubiquitylation and degradation
we discuss the evidence and set realistic expectations
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