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Size and surface area The size of AgNPs is a critical determinant of their antimicrobial activity, as it directly affects their surface-area-to-volume ratio and interaction with bacterial cells

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doi: 10.1038/s41568-019-0222-9

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In cholangiocarcinoma, combined BET degradation and mTOR inhibition synergistically reduce acetylation of PSAT1-associated H3K27, inducing PSAT1 downregulation and subsequent dysfunction of the serine-glycine-one-carbon (SGOC) pathway (114)