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In some embodiments, a low viscosity otic formulation or device described herein provides an apparent viscosity of from about 500 cP to about 10,000 cP

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This makes physiological sense since the peptide can enhance healing capacity, but the tissue still needs appropriate loading stimulus to remodel properly

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Limitations and Challenges Related to the Use of Peptides Incorporated in Wound Dressings Despite their promising therapeutic potential, peptide-based wound dressings face a number of scientific, technical, regulatory, and clinical limitations that hinder their widespread adoption in clinical practice

None of this is meant to alarm, only to mark the edges