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Clinical and molecular characterization of Rubinstein-Taybi syndrome patients carrying distinct novel mutations of the EP300 gene

We identified that the combination of sertraline and chloroquine effectively and synergistically restricts GBM cell proliferation and reduces the clonogenic capacity of GBM cell lines and patient-derived GBM cell models

It can also be made in a lab into a dietary supplement, which is used widely in alternative medicine

Li, J.-J

Oral is often preferred for convenience and gut-specific studies, while injectable offers higher bioavailability for systemic or targeted musculoskeletal research

et al., 2023) designed a high-performance multi-dynamic bond cross-linked hydrogel, siRNA@G5-PBA@Gel, which controls gene expression in a spatiotemporal manner to achieve gene-cell combination therapy for IDD (Figure 9)