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Description
MSCs are nonhematopoietic, multipotent stem cells that can differentiate into various mesodermal lineages and modulate the immune system
1a with representative placental images depicted in Supplemental Fig

Vourdoumpa, E

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A recent study revealed that TDP-43 accumulation within stress granules, together with oxidative stress, collectively induces intra-condensate demixing, leading to a TDP-43-enriched phase that forms pathological cytoplasmic aggregates (Yan et al., 2025)
These effects resulted in increased NSC deficiency and therefore a reduced repair response (Ding et al., 2025)