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There is already a strong relationship between alcoholism and depression, and many people drink to try and deal with depressive symptoms

The research demonstrated that treating these patients with a nebulized, multi-ingredient antioxidant agent containing NAC led to parallel increases in healthy T-cell cytokine production and a highly significant mean 54% reduction in self-reported symptom severity over several months

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The distinction matters because treatment differs: intrinsic factor deficiency requires parenteral B12, whilst dietary deficiency often responds to oral supplementation or dietary modification