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Proc Natl Acad Sci U S A 99(10):67556760 Odorizzi G, Babst M, Emr SD (1998) Fab1p PtdIns(3)P 5-kinase function essential for protein sorting in the multivesicular body

Ramires PR, Ji LL
c-MET controls multiple biological functions, including proliferation, survival, motility and invasion, which, when dysregulated by aberrant c-MET activation, can lead to both tumor growth and metastatic progression of cancer cells

Phase II clinical trials for inflammatory bowel disease reported no toxicity or adverse events in treated patients, though detailed safety data from these trials have not been published in peer-reviewed literature

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