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PANoptosis is a distinct innate immune-mediated inflammatory lytic cell death pathway initiated by pattern-recognition receptors and propagated via the PANoptosome complex, which plays a critical hub role in the interactive regulation between immunometabolic dysregulation and inflammatory programmed cell death in diabetes

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The patient can be relieved by appropriate diet, probiotics, and antibiotic use in this condition, which is defined as excessive bacterial growth in the small intestines

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