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For instance, TEPP-46 and microbial metabolite-based therapies (e.g., butyrate, itaconate) exhibit robust efficacy in animal models but have yet to be systematically evaluated in human autoimmune populations

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When the temperature is shifted 27C, the 405/488 nm ratio does not change significantly in the root, while a mild increase is observed after 45 minutes of treatment (Figure 1A, C, E and G)

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