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These results imply that pFeSAN may mediate the complete O 2 -to-water reduction without the release of free ROS during oxidation, analogy with the catalytic pathways of natural C c O (Fig

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JAMA 324 , 20762094 (2020)

Afterwards, the cells were blocked, permeabilized and incubated with primary mouse monoclonal antibody to H2AX (Ser-139) at 1 : 1000 (Upstate Biotechnology, Upstate, NY, USA) and diluted 1 : 500 for 1 h at room temperature, followed by incubation with anti-mouse FITC secondary antibody (Sigma-Aldrich) that was diluted 1 : 200 for 1 h at room temperature

Furthermore, the synthesis of asparagine from glutamine within tumor cells can impact the production of nucleotides by modulating serine levels [61]