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We observed, especially in the central region, an increase in TUNEL-positive cells in mutant growth plates, indicative of cell death (Fig

Photoreceptor membranes containing polyunsaturated fatty acids susceptible to photooxidation occur in the retina at high oxygen tension and under chronic light exposure

Figure 1 Important developments in the field over this time include the first clinical descriptions of the inborn error of metabolism disorder homocystinuria and the subsequent discovery of severe genetic defects in enzymes involved in homocysteine metabolism as causative factors (4)

miR-106b suppresses pathological retinal angiogenesis

Results Intra- and extracellular changes in redox-balance in lung cancer To address the impact of oxidative stress on tissue redox signaling in cancer we carried out redox proteomics profiling of 70 matched healthy and lung tumor tissue pieces which, upon site annotation and after filtering for valid values (see Materials and methods), enabled us to quantitatively address the oxidative status of 1834 individual cysteine residues across 921 different proteins (Supplementary Data 3)

Seminal plasma total antioxidant capacity and vitamin-C levels in asthenozoospermia: a case-control study