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Therefore, enhanced glutaminolysis might eventually contribute to the initiation and progression of cancer by stimulating cell growth via the mTORC1 pathway and enhancing aerobic glycolysis while disrupting the proper elimination of misfolded proteins, damaged DNA and organelles through the inhibition of autophagy and the DNA damage response 166

Meprin expression modulates the interleukin-6 mediated JAK2-STAT3 signaling pathway in ischemia/reperfusion-induced kidney injury

Establishment of live-cell-based coupled assay system for identification of compounds to modulate metabolic activities of cells

BW: Writing review & editing, Formal analysis, Supervision

This is supported by the deleterious effect of a peroxisomal MDHAR mutant [191]

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