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Studies have reported OCTN2 expression in respiratory epithelial cells and alveolar macrophages, which is especially high in the upper lung region [301], and OCTN2-mediated carnitine uptake plays an important role in maintaining respiratory cilia beating and airway mucociliary clearance function, helping to remove excess mucus and potentially harmful substances from the airway [302]

However, intense evidences suggest that lipid peroxidation can be the common feature that initiates and propagates the cell death

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However, treatments that lower plasma triglycerides have not been consistently shown to reduce cardiovascular outcomes
