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Synergistic antimicrobial activities of epigallocatechin gallate, myricetin, daidzein, gallic acid, epicatechin, 3hydroxy6methoxyflavone and genistein combined with antibiotics against ESKAPE pathogens

Reconstitution does not alter the in vivo dihexa half life (which is determined by metabolism and clearance), but it significantly affects ex vivo peptide stability before administration

R., Beauchamp, G

Starting with a known quantity and quality is the first step toward reliable research

Thats the promise of Smart Brothers Dihexa, a peptide (also called PNB-0408) that crosses the blood-brain barrier, binds hepatocyte-growth-factor (HGF) with femtomolar affinity, and turbo-charges HGF/TrkB signallingseven orders of magnitude more potent than BDNF itself

BJOG An Int