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Die genaue orale Bioverfgbarkeit wurde nicht formal bestimmt, aber die nach oraler Gabe beobachteten systemischen Wirkungen deuten auf eine signifikante Absorption hin

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This oxidative stress damages cellular membranes, proteins, and DNA

In primary cultures of cortical neurons and astrocytes, inhibition of 26S proteasome activity by lactacystin (a non-peptidic proteasome inhibitor) resulted in a remarkable decrease in A42 degradation