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And in a mouse model with a genetic deletion of GPX4, MK-4 showed a protective effect on tissues (Mishima et al., 2022)
It also inhibited the rise in A-peptide levels, astrocyte activation, and inflammatory proteins involved in astrocyte activation and amyloidogenesis [49]
Survival and causes of death in thalassaemia major
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However, data are limited to preclinical studies
