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For example, during cancer chemotherapy, resistant clones can arise and expand, contributing to cancer recurrence and metastasis 1,2,3,4

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Oxidative Medicine and Cellular Longevity, 2018, 9630175

Adv Exp Med Biol 1:5976 Hope M, Saxby T (2007) Tendon healing

But if a patient suffers from conditions that prevent him from absorbing the vitamin from his diet, a lifelong intake is commonly required for health