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Here we show the development, characterization, and in vitro and in vivo evaluation of a new composite material for local therapy of GBM post-surgery

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Future medicinal chemistry efforts may yield next-generation compounds with enhanced properties, including improved tissue selectivity, modified pharmacokinetics, or additional mechanistic activities that complement NNMT inhibition

The structure of the E-domains has not been resolved, and their molecular functions are still unclear

Female infertility is a major public health concern and a global challenge

The typical adult dosage required is 500 mg three to four times daily