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David Perlmutter, a neurologist at The Perlmutter Health Center, oversaw a human pilot study on the use of IV glutathione for PD, the results of which he published in Movement Disorders

[DOI] [PubMed] [Google Scholar] 185.Gumpricht E., Devereaux M.W., Dahl R.H., Sokol R.J

While vitamin D is central to calcium absorption and bone integrity, vitamin B12 is crucial for neuroprotective effects and maintaining healthy red blood cells

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IKK then phosphorylates IkBa (adds a phosphorus to it, a common way to activate a molecule from an inert state) IkBa is degraded and releases NF-kB, which is now free to translocate to the nucleus It does so through its subgroups p50 and p65 Having done so, it will bind to various DNA sites (gene transcription) and trigger the DNA to generate inflammatory signalling molecules such as IL-6, IL-8, TNF, etc

In line with these findings, human Parkinsons patients with bacterial overgrowth in the small intestine show reduced Parkinsonian symptoms after antibiotic treatment (Fasano et al., 2013)