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These injections deliver a synthetic form of cortisol, a naturally occurring hormone in the body, directly into the affected joint or soft tissue

The nanoparticles release KGF to decrease intrapulmonary ECM in fibrotic lesions, while MMP13 mRNA is delivered in integrinenriched myofibroblasts and injured AT2 cells to reepithelialize the disrupted alveolar epithelium, synergistically improving lung function and reversing pulmonary fibrosis in mice

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These friable masses consist of fibrin, inflammatory cells, and microorganisms, typically forming on the valve leaflets

Ultrastructurally, these are seen as characteristic membranous cytoplasmic bodies, consisting of concentric membranous whorls with a periodicity of about 5 nm (Fig