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Inhibition of either system leads to increased levels of -synuclein, and some evidence suggests that there is compensatory crosstalk between the two systems

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Not only does Nrf2 prevent normal cells from becoming cancerous, but it also helps cancer cells survive in harmful environments

Studies have shown that Pip6a-PMO effectively rescues the disease phenotype and improves the survival rate of severe SMA mice, showing strong efficacy in the central nervous system and peripheral tissues

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