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doi: 10.2337/diabetes.54.8.2390

When to seek medical attention: Patients should call 999 immediately for severe allergic reactions (facial swelling, breathing difficulties, widespread rash)

Vitamin B12 supplements can help treat or prevent a vitamin B12 deficiency, which can be serious and Not everyone needs to take a vitamin B12 supplement, as However, healthcare professionals may recommend vitamin B12 supplements for certain populations, including: people following a vegan diet older adults people who have had gastrointestinal surgery people who have nutrient absorption issues people with dietary restrictions People taking certain long-term medications, such as metformin and proton pump inhibitors, may also benefit from a supplement, as these medications can affect absorption of vitamin B12

If possible, it is best to take the injection on an empty stomach

In addition, some suggested that serum holo-transcobalamin may be a more valid marker of vitamin B-12 status during pregnancy than the markers we used (43)