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Paclitaxel nanoparticles induce apoptosis and regulate TXR1, CYP3A4 and CYP2C8 in breast cancer and hepatoma cells

Yet, to conduct more reasonable trials, a deeper understanding of their mechanisms of action and the chemical structures of nanocarriers is essential

Khorram O et al

The glutathione level can be replenished with IV therapy to restore these depleted levels quickly, which is not possible with oral glutathione supplementation

10.1007/s11010-011-1104-y 135 RajabiZ.YazdekhastiH.Noori MugahiS

GSH depletion and concomitant increase in O&NS and mitochondrial dysfunctions play a role in the pathophysiology of diverse neuroimmune disorders, including depression, myalgic encephalomyelitis/chronic fatigue syndrome and Parkinsons disease, suggesting that depleted GSH is an integral part of these diseases