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Nayan Patel [00:06:51]: Very early on, we figured that portion out
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Rothstein for glutamate transporter antibodies

Okuyama et al., 2015

On the one hand, IL-1 exacerbates BBB disruption by downregulating tight junction protein Zonula Oc-cludens-1 (ZO-1), activating caspase-1 within the brain, and establishing a positive feedback loop that amplifies IL-1 production (36)

The pathophysiology of the GFR reduction remains ill defined

In particular, detoxification capacity and drug metabolism can differ between individuals
