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Description
269 BCAA uptake is dependent on the type I amino acid transporter LAT, and mutations in SLC7A5 and SLC3A2, members of the LAT family, impair BCAA uptake by T cells and inhibit the proliferation and differentiation of Th1, Th17, and CTL cells
This inhibition prevents fatty acid breakdown while synthesis occurs
From these measurements we could not observe any significant change in phenotype with respect to untreated worms (Figure S4)
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Erickson, C
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