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Orforglipron (LY3502970), a novel, oral non-peptide glucagon-like peptide-1 receptor agonist: a phase 1a, blinded, placebo-controlled, randomized, single- and multiple-ascending-dose study in healthy participants

and the National Natural Science Foundation of China (Grant No

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However, these strategies are still not available for clinical treatments and face numerous challenges, such as the stability of drug delivery systems, long-term safety, and the feasibility of clinical translation

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