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Impaired retrograde axonal transport of BDNF and its cognate receptor, tropomyosin-related receptor kinase-B (TrkB), from the brain to RGC somas has been implicated in the progressive and selective degeneration of the ganglion cell layer and optic nerve in glaucomatous models [145, 146]

In the future, with the in-depth study of UC disease mechanisms and the development of more innovative drugs, more precise and personalized treatments with multiple targets, such as the combination of conventional drugs, conventional drugs and biologics, and biologics and biologics, are expected to be developed

Antioxidant protection against environmental stress

In addition, enhanced phasic GABAergic signaling has been found in cortical layer 5 of the peri-infarct area during the first and second week of the recovery phase of stroke (Hiu et al., 2016